Sulfadoxine-Pyrimethamine with Amodiaquine (SPAQ)

Photo: Toby Madden/MMV

SMC is administered using co-blistered sulfadoxine-pyrimethamine (SP) together with amodiaquine (AQ). This combination was chosen due to its ability to provide relatively long-lasting protection. SPAQ is currently dosed at monthly intervals for three to four months during the rainy season. This combination is a successful example of the re-purposing of two antimalarial drugs.